People say psoriasis is often depressed, but not more than a control population. However, living with chronic disease and displayed on the psychological repercussions and led to a decline in self-esteem. Psoriasis appears as much influence on the depressed mood of major chronic diseases whose prognosis is bad. In addition, both seem to stress involved in the outbreak of psoriasis in recidivism. At the neurological, people who develop psoriatic neuro-degenerative disease like Alzheimer's, often see their psoriasis lesions disappear.