Several women who undergo estrogen replacement had experience heart attacks than those women in a group that did not go through estrogen replacement. Many women are now cautious to such treatment for hot flashes and other menopausal symptom because of this side effect that could lead into more serious complications.

This is also the reason why they choose the use of herbal medication to alleviate struggling against hot flashes and other menopausal symptoms, because it is made from all natural ingredients.